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COVID-19 (SARS-CoV-2) Reagent Raw Material

Features

  • A series of products for SARS-CoV-2 and its mainstrain variants detection and differentiation
  • Short product development cycle, efficient delivery
  • Comprehensive coverage of different methodologies, eliable and stable product performance
  • Service supported by a highly efficient, full-service team


B.1.1.7 Variant Strain Detection

This innovative product consists of a monoclonal antibody pair to differentiate the SARS-CoV-2 wide-type strain and the B.1.1.7 variant strain N protein. The antibody pair uses two different antibodies for immunoassay of test samples. These antibody pairs can detect B.1.1.7 and B.1.351 variants while having a consistent reaction to the wild-type virus. With the advantages of rapidity, low cost and high efficiency, this product can ensure the rapid and accurate detection of the B.1.1.7 variant strain.

Recommended Pair

Catalog No.

Source

Clone

Isotype

Application

Applicable Platform

Pair 1

FPZ0574

Mouse

8F5

IgG1

Conjugate

Lateral Flow

FPZ0546

5E7

Coating Ab 1 (T1)

FPZ0649

2D6

Coating Ab 2 (T2)


E484K Variant Strain Detection

The E484K is a mutation found in multiple COVID-19 variants that resists recognition by antibodies and helps SARS-CoV-2 bypass immune protection of prior infection or vaccination, potentially weakening the effectiveness of vaccines. Fapon Biotech used E484K mutant strain recombinant RBD antigen to detect the antibody escape phenomenon produced by the non-E484K mutant strain infection. This product applies the POCT methodology to offer a rapid, effective and low-cost testing option to distinguish patients from E484K and non-E484K mutant strain infection.

Catalog No.

Product Description

Purity

Application

FPZ0556

Non-E484K mutant strain recombinant RBD antigen

≥90%

Coating antigen 1 (T1)

FPZ0655

E484K mutant strain recombinant RBD antigen

Coating antigen 2 (T2)

GECACE2S102

ACE2 antigen

Conjugate


COVID-19 Neutralizing Antibody Test

Neutralizing antibodies (NAbs) have significant preventive and therapeutic effects. They mainly target the RBD region and can block the binding site of COVID-19 to the ACE2 receptor. COVID-19 NAbs are low in content and highly specific, which play a crucial role in the research of COVID-19 treatments. Meanwhile, they can measure the titer level of the immune response after vaccination, being an essential tool of vaccine effectiveness evaluation. After several verifications, Fapon NAb test raw materials have good qualities in affinity, sensitivity, specificity, and correlation to sVNT (Surrogate Virus Neutralization Test), which can be applied in antibody-drug studies, vaccine potency assays, and more.

Catalog No.

Source

Tag

Buffer System

Applicable Platform

GECACE2S101

CHO

His

10mMPB+150mMNaCl, pH7.4

ELISA/CLIA/CMIA

GECACE2S102

CHO

hFC

10mMPB+150mMNaCl, pH7.4

ELISA/CLIA/CMIA/Lateral Flow/Immunofluorescence

FPZ0533

E.coli

His

10mMPB+150mMNaCl, pH7.4

Lateral Flow

FPZ0557

CHO

mFC

10mMPB+150mMNaCl, pH7.4

ELISA/CLIA/CMIA

FPZ0537

CHO

His

10mMPB+150mMNaCl, pH7.4

ELISA/CLIA/CMIA

FPZ0556

CHO

His

10mMPB+150mMNaCl, pH7.4

Lateral Flow/Immunofluorescence

GEEACE2S101

CHO

His

10mMPB+10% NBS+50% glycerol+0.1% P300, pH7.

ELISA

GEEACE2S102

CHO

hFC

10mMPB+10% NBS+50% glycerol+0.1% P300, pH7.

ELISA

FPZ0565

CHO

mFC

10mMPB+10% NBS+50% glycerol+0.1% P300, pH7.

ELISA

FPZ0540

CHO

His

10mMPB+10% NBS+50% glycerol+0.1% P300, pH7.

ELISA


COVID-19 Antigen Test

The nucleocapsid (N) is a major structural protein of SARS-CoV. It is highly conservative, providing an ideal marker for immunodiagnosis. Fapon self-developed monoclonal antibodies have high sensitivity, specificity and batch-to-batch consistency, no cross-reactivity with other pathogens (human coronaviruses, flu, pneumonia, etc.). Different application scenarios are supported with stable bulk commercial volume. The featured solution provides custom reagent development and bulk reagent component services, adding high values to diagnostic kit development.


Recommended Pairs

Catalog No.

Source

Clone

Isotype

Application

Applicable Platform

Pair 1

FPZ0638

CHO

31F11

IgM

Coating

Lateral Flow/Immunofluorescence

FPZ0639

CHO

31F12

IgM

Conjugate

Lateral Flow/Immunofluorescence

Pair 2

FPZ0546

Mouse

5E7

IgG1

Coating

Lateral Flow/Immunofluorescence

/CLIA/CMIA

FPZ0573

Mouse

8A8

IgG

Conjugate

Pair 3

FPZ0546

Mouse

5E7

IgG1

Coating

FPZ0574

Mouse

8F5

IgG

Conjugate

Pair 4

FPZ0548

Mouse

5F9

IgG1

Coating

FPZ0546

Mouse

5E7

IgG1

Conjugate

Pair 5

FPZ0550

Mouse

5F1

IgG1

Coating

Lateral Flow /Immunofluorescence

FPZ0554

Goat

--

--

Conjugate

Pair 6

FPZ0547

Mouse

3B6

IgG1

Coating

FPZ0554

Goat

--

--

Conjugate

Pair 7

FPZ0549

Mouse

5E4

IgG1

Coating

CLIA/CMIA

FPZ0546

Mouse

5E7

IgG1

Conjugate

Pair 8

FPZ0554

Goat

--

--

Coating

FPZ0546

Mouse

5E7

IgG1

Conjugate

Pair 9

FPZ0574

Mouse

8F5

IgG

Coating

FPZ0599

Mouse

8B3

IgG

Conjugate



COVID-19 Antibody Test

High sensitivity and specificity n/s protein antigens for IgM, IgG and neutralizing antibody detection. Outstanding performance rewarded positive feedbacks and extensive application from customers.

Applicable Methodology

Catalog No.

Source

Epitope

Recommended Application

Lateral Flow/Capture

FPZ0515

E.coli

N Protein

Conjugate

FPZ0516

E.coli

N Protein

FPZ0517

E.coli

N Protein

FPZ0564

E.coli

N Protein

FPZ0533

E.coli

S Protein (His)

FPZ0557

CHO

S Protein (mFC)

FPZ0537

CHO

S Protein (His)

Lateral Flow/Indirect

FPZ0515

E.coli

N Protein

Coating

FPZ0516

E.coli

N Protein

FPZ0517

E.coli

N Protein

FPZ0555

CHO

S Protein (His)

Lateral Flow/Sandwich

FPZ0533

E.coli

S Protein (His)

Conjugate

FPZ0556

CHO

S Protein (His)

Coating

ELISA/Indirect

FPZ0512

E.coli

N Protein

Coating

FPZ0513

E.coli

N Protein

FPZ0514

E.coli

N Protein

FPZ0537

CHO

S Protein (His)

FPZ0555

CHO

S Protein (His)

ELISA/Capture

FPZ0521

E.coli

N Protein

Conjugate

FPZ0540

CHO

S Protein

Conjugate

ELISA/Sandwich

FPZ0537

CHO

S Protein (His)

Coating

FPZ0540

CHO

S Protein

Conjugate

CLIA/Indirect

FPZ0515

E.coli

N Protein

Coating

FPZ0516

E.coli

N Protein

FPZ0517

E.coli

N Protein

FPZ0537

CHO

S Protein (His)





COVID-19 IgM & IgG Quality Control

Fapon Anti-SARS-CoV-2 fully human RBD monoclonal antibody and N protein humanized monoclonal antibody outperform positive specimens by exhibiting higher stability, specificity and affinity. They are safe to handle with non-infectious, providing a valuable tool to reagent development, validation, and production.

Catalog No.

Description

Application

FPZ0570

Fully Human RBD IgG Monoclonal Antibody

Quality Control

FPZ0584

Fully Human RBD IgM Monoclonal Antibody

FPZ0589

Fully Human RBD IgM Monoclonal Antibody



COVID-19 Secondary Antibody

Universal secondary antibodies feature high sensitivity, specificity and wide application. Large volume supplied with stable quality which has been widely validated and recognized by IVD manufacturers.

Catalog No.

Source

Application

Applicable Platform

GRCIGMC101

Mouse

Coating/Conjugate

ELISA/Lateral Flow/Immunofluorescence

GRCIGMC104

Mouse

Coating/Conjugate

Lateral Flow/Immunofluorescence

BENIGGI103

BRCIGGS101

BENIGGI107

BEEIGMI101

Mouse

Conjugate

ELISA

BEEIGGI102

GRCGAMS002

Goat

Coating

Lateral Flow/Immunofluorescence


COVID-19 Nucleic Acid Test

Product collection includes RT-PCR mixes, enzymes, high throughput sequencing test components, etc. With features in easy to use, high sensitivity and low containment risk, they can be applied in nucleic acid detection reagent for COVID-19 prevention and control.


RT-PCR Mix

Catalog No

Description

Advantage

MD013

Anstart One-Step RT-PCR Mix

Efficient, convenient, stable, achieve multi-target detection and amplification

MD027

Hotstart HiTaq One-Step RT-PCR Mix

MDR-S151

Hotstart Taq One-Step RT-PCR Mix

MD013P

Anstart One-Step RT-PCR Mix (Heat-labile UDG)

Anti-pollution system adds to One-Step RT-PCR Mix to lower contamination effectively

MD027P

Hitaq One-Step RT-PCR Mix (Heat-labile UDG)

MDR-S151P

Hotstart Taq One-Step RT-PCR Mix (Heat-labile UDG)

NCK013-DR2-F10

COVID-19 Direct One-Step RT-PCR Components

Extraction of the nucleic acid sample completes in ± 5 min, amplification and testing completes in 2 h


Enzyme

Catalog No

Description

Advantage

MD028

Super M-MuLV Reverse Transcriptase

High specificity & RT efficiency

MD311

Mutiscript II Reverse Transcriptase

High activity & stability

MD026

HiTaq DNA polymerase

High stability & specificity

MD006

Anstart Taq DNA Polymerase

MD099

AK Taq DNA Polymerase

Highly active and specific of variant strain detection, strong tolerance to impurities, compatible with direct amplification

MD015

RNasin (RNase Inhibitor)

High specific, activity & stability

MD014

Uracil-DNA Glycosylase (UDG)

Inactivation at 95°C, PCR cross-contamination & cross-amplification control

MD029

Heat-labile Uracil-DNA Glycosylase

Inactivation at 55°C, sensitive to heat & high purity

MD030

Bst DNA Polymerase

High purity & activity

MD031

Phi29 DNA Polymerase

Excellent strand replacement & synthesis


High Throughput Sequencing

Catalog No

Description

Advantage

NK002

Fapon Two-step Library Prep Kit for Illumina

For genomic DNA & mNGS libraries construction

NK004

Fapon Two-step Library Prep Kit for Ion Torrent

NK202

Rapid Stranded RNA-seq Library Prep Kit for Illumina

For the entire process of constructing RNA libraries including modules for RNA fragmentation, cDNA synthesis, library amplification and purification

NM022

cDNA Synthesis Kit

For mNGS libraries construction


PCR Supplementary Material

Catalog No

Description

Advantage

MD016

25mM dNTP Mix

High purity

MD016M

25mM dN(U)TP Mix

MD016L

20/40mM dN(U)TP Mix

MD025

Proteinase K